Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028487 | 0.86 | TSHR (0.48) | MAPTRAB9ARXFP1KMT2AALDH1A1 | |
| SCHEMBL10015973 | 0.85 | MAPT (0.44) | MAPTRAB9ARXFP1KMT2AALDH1A1 | |
| SCHEMBL11024065 | 0.84 | MAPT (0.46) | MAPTRAB9ARXFP1KMT2AALDH1A1 | |
| SCHEMBL13777633 | 0.84 | MAPT (0.47) | MAPTRAB9ARXFP1KMT2AALDH1A1 | |
| SCHEMBL7203836 | 0.83 | RAB9A (0.60) | MAPTRAB9ARXFP1KMT2AALDH1A1 | |
| SCHEMBL227301 | 0.83 | HCAR2 (0.51) | ALDH1A1LMNATSHR | |
| SCHEMBL8571160 | 0.82 | IDO1 (0.53) | MAPTRAB9AALDH1A1MAOBPOLB | |
| SCHEMBL11632216 | 0.82 | RAB9A (0.62) | MAPTRAB9ARXFP1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11632213 | 0.81 | RAB9A (0.61) | MAPTRAB9ARXFP1KMT2AALDH1A1 | |
| SCHEMBL1493670 | 0.81 | KMT2A (0.60) | MAPTRAB9ARXFP1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110551057-B | Chiral 3,3-disubstituted oxindole derivative and synthesis method and application thereof | 华东师范大学 | 2023-02-07 | — | — | CN | disclosed |
| CN-110551057-A | Chiral 3, 3-disubstituted oxindole derivative and synthesis method and application thereof | UNIV EAST CHINA NORMAL | 2019-12-10 | — | — | CN | disclosed |
| EP-0067954-B1 | ORGANIC PHOTOCONDUCTIVE COMPOSITIONS FOR ELECTROPHOTOGRAPHY | KABUSHIKI KAISHA TOSHIBA (JP) | 1985-08-28 | — | — | EP | disclosed |
| EP-0067954-A2 | Organic photoconductive compositions for electrophotography | KABUSHIKI KAISHA TOSHIBA (JP) | 1982-12-29 | — | — | EP | disclosed |