Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.47 |
| ▸ | VCP | P55072 | 5/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL73543 | 0.84 | AOC3 (0.47) | CHRNA7 | |
| SCHEMBL27367437 | 0.82 | DRD2 (0.52) | HRH4HRH3HTR2ACHRNA7HTR7 | |
| SCHEMBL15219331 | 0.81 | HRH4 (0.55) | HRH4HRH3 | |
| SCHEMBL12993141 | 0.81 | CYP2A6 (0.44) | HRH4HRH3CHRNA7HTR7ADRA1B | |
| SCHEMBL3640169 | 0.81 | AOC3 (0.44) | HTR7ADRA1B | |
| SCHEMBL27502681 | 0.81 | GRIN2B (0.54) | HRH4HRH3CHRNA7VCPHTR7 | |
| SCHEMBL10441226 | 0.80 | AOC3 (0.42) | HTR7ADRA1B | |
| SCHEMBL13313599 | 0.79 | HRH4 (0.49) | HRH4HRH3HTR2ACHRNA7VCP | |
| SCHEMBL7503773 | 0.79 | HRH4 (0.52) | HRH4 | |
| Bromide SCHEMBL7870782 | 0.79 | HRH4 (0.50) | HRH4HRH3VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608079-B1 | Activating serotonin-1F receptors, inhibiting neuronal protein extravasation, treating migraine | ELI LILLY AND COMPANY | 2003-08-19 | — | — | US | disclosed |