Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203954 | 0.82 | HRH4 (0.53) | HTR2AHRH3HRH4CHRNA7HTR7 | |
| SCHEMBL20284611 | 0.81 | HRH4 (0.45) | DRD2HTR2AHTR2CKCNH2PARP1 | |
| SCHEMBL6650886 | 0.81 | DRD2 (0.48) | DRD2HTR2AHTR2CKCNH2PARP1 | |
| SCHEMBL3640169 | 0.80 | AOC3 (0.44) | KDM4EHTR7ADRA1B | |
| SCHEMBL2789326 | 0.80 | AKR1C3 (0.49) | HRH3HRH4KDM4EAKR1C3 | |
| SCHEMBL2009005 | 0.79 | CCNT1 (0.52) | KCNH2HRH3HRH4CCNT1CDK9 | |
| SCHEMBL10441226 | 0.78 | AOC3 (0.42) | KDM4EHTR7ADRA1B | |
| SCHEMBL13634946 | 0.77 | CHRNB2 (0.50) | HTR2AHTR2CKCNH2HRH3PARP1 | |
| SCHEMBL73543 | 0.76 | AOC3 (0.47) | CHRNA7KDM4E | |
| SCHEMBL7899970 | 0.76 | HPGDS (0.51) | PARP1KDM4EAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059951-A1 | INHIBITORS OF THE ANDROGEN RECEPTOR DNA-BINDING DOMAIN | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2024-03-28 | — | — | WO | disclosed |