Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 20/20 | 0.68 |
| ▸ | DRD2 | P14416 | 19/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 18/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5098219 | 0.94 | DRD3 (0.76) | DRD3DRD2KCNH2 | |
| Hydrochloric Acid SCHEMBL5110985 | 0.93 | DRD3 (0.75) | DRD3DRD2KCNH2 | |
| SCHEMBL5098335 | 0.81 | DRD3 (1.00) | DRD3DRD2KCNH2 | |
| SCHEMBL5102344 | 0.80 | DRD2 (0.38) | DRD3DRD2KCNH2 | |
| SCHEMBL5110767 | 0.79 | DRD3 (0.63) | DRD3DRD2KCNH2 | |
| SCHEMBL4879674 | 0.79 | DRD3 (0.91) | DRD3DRD2KCNH2 | |
| Hydrochloric Acid SCHEMBL4879731 | 0.79 | DRD3 (0.89) | DRD3DRD2KCNH2 | |
| SCHEMBL5104734 | 0.72 | DRD3 (0.77) | DRD3DRD2KCNH2 | |
| SCHEMBL4770243 | 0.71 | DRD3 (0.80) | DRD3DRD2KCNH2 | |
| SCHEMBL5110871 | 0.70 | DRD3 (1.00) | DRD3DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335915-A2 | TETRAHYDROBENZAZEPINE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS (ANTIPSYCHOTIC AGENTS) | SMITHKLINE BEECHAM PLC (GB) | 2003-08-20 | — | — | EP | disclosed |
| WO-2002040471-A9 | TETRAHYDROBENZAZEPINE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS (ANTIPSYCHOTIC AGENTS) | SMITHKLINE BEECHAM PLC (GB) | 2003-07-31 | — | — | WO | disclosed |
| WO-2002040471-A2 | TETRAHYDROBENZAZEPINE DERIVATIVES USEFUL AS MODULATORS OF DOPAMINE D3 RECEPTORS (ANTIPSYCHOTIC AGENTS) | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-05-23 | — | — | WO | disclosed |