Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | RGS12 | O14924 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166663 | 0.86 | KMT2A (0.48) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL4482998 | 0.85 | KMT2A (0.77) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL4483004 | 0.85 | KMT2A (0.77) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5157754 | 0.83 | KMT2A (0.52) | KMT2AMEN1MAPTSMN1; SMN2GAA | |
| SCHEMBL7205283 | 0.83 | KMT2A (0.56) | KMT2AMEN1MAPTSMN1; SMN2GAA | |
| SCHEMBL5157804 | 0.78 | LMNA (0.48) | KMT2AMEN1MAPTGAAPOLB | |
| SCHEMBL7204118 | 0.77 | MEN1 (0.61) | KMT2AMEN1MAPTSMN1; SMN2GAA | |
| SCHEMBL5159075 | 0.75 | KMT2A (0.49) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL7166665 | 0.75 | MAPT (0.54) | KMT2AMEN1MAPTSMN1; SMN2GAA | |
| SCHEMBL4487339 | 0.74 | KMT2A (0.74) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003531133-A | — | — | 2003-10-21 | — | — | JP | claimed |
| EP-1272457-A2 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC Research and Development Limited Partnership (CA) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079158-A2 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2001-10-25 | — | — | WO | claimed |