Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.61 |
| ▸ | MAOB | P27338 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166665 | 0.94 | MAPT (0.54) | MEN1KMT2AMAPTALOX5MAOB | |
| SCHEMBL6030512 | 0.85 | MEN1 (0.78) | MEN1KMT2AMAPTALOX5MAOB | |
| SCHEMBL4483006 | 0.85 | MEN1 (0.78) | MEN1KMT2AMAPTALOX5MAOB | |
| SCHEMBL5176964 | 0.84 | DNM1 (0.44) | MEN1KMT2AMAPTALOX5ALDH1A1 | |
| SCHEMBL7205287 | 0.83 | MAPT (0.47) | MEN1KMT2AMAPTALOX5MAOB | |
| SCHEMBL5159075 | 0.81 | KMT2A (0.49) | MEN1KMT2AMAPTALOX5ALDH1A1 | |
| SCHEMBL6029881 | 0.80 | MAPT (0.69) | MEN1KMT2AMAPTALOX5MAOB | |
| SCHEMBL4486799 | 0.80 | MAPT (0.69) | MEN1KMT2AMAPTALOX5MAOB | |
| SCHEMBL13678117 | 0.79 | MAPT (0.68) | MEN1KMT2AMAPTALOX5MAOB | |
| SCHEMBL5234290 | 0.78 | MET (0.47) | MEN1KMT2AMAPTMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003531133-A | — | — | 2003-10-21 | — | — | JP | claimed |
| EP-1272457-A2 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC Research and Development Limited Partnership (CA) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079158-A2 | COMPOUNDS FOR MODULATING CELL PROLIFERATION | HSC RESEARCH AND DEVELOPMENT LIMITED PARTNERSHIP (CA) | 2001-10-25 | — | — | WO | claimed |