⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26404 | 0.91 | — | — | |
| Ammonia Solution, Strong SCHEMBL27991631 | 0.88 | — | — | |
| SCHEMBL27626913 | 0.88 | — | — | |
| Bromide SCHEMBL3286873 | 0.85 | — | — | |
| SCHEMBL2178206 | 0.82 | TTR (0.35) | — | |
| Benzene SCHEMBL28308833 | 0.82 | — | — | |
| Acetamide SCHEMBL720429 | 0.81 | LMNA (0.40) | — | |
| SCHEMBL25941 | 0.79 | — | — | |
| SCHEMBL14321619 | 0.79 | — | — | |
| SCHEMBL6467586 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240442-B1 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | MEDICHEM KOREA CO LTD (KR) | 2012-06-20 | — | — | EP | disclosed |
| US-8124790-B2 | Preparation process useful in synthesis of atorvastatin | MEDICHEM KOREA CO., LTD. (KR) | 2012-02-28 | — | — | US | disclosed |
| US-20110112309-A1 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | MEDICHEM KOREA CO., LTD. (KR) | 2011-05-12 | — | — | US | disclosed |
| EP-2240442-A2 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | Medichem Korea. Co., Ltd. (KR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009084773-A2 | PREPARATION PROCESS USEFUL IN SYNTHESIS OF ATORVASTATIN | MEDICHEM KOREA. CO., LTD. (KR) | 2009-07-09 | — | — | WO | disclosed |