SCHEMBL2178206

SCHEMBL2178206

CCC1OCCOCCO1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TTR P02766 1/20 0.35
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM5 P08912 1/20 0.33
CHRM3 P20309 1/20 0.33
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26404 0.91
Ammonia Solution, Strong SCHEMBL27991631 0.88
SCHEMBL27626913 0.88
Bromide SCHEMBL3286873 0.85
Ethylamine SCHEMBL720431 0.82
Benzene SCHEMBL28308833 0.82
SCHEMBL14321619 0.79
SCHEMBL25941 0.79
Acetamide SCHEMBL720429 0.76 LMNA (0.40)
SCHEMBL6467586 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9388105-B2 Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals EASTMAN CHEMICAL COMPANY (US) 2016-07-12 US claimed
US-8969598-B2 Production of cyclic acetals or ketals using liquid-phase acid catalysts EASTMAN CHEMICAL COMPANY (US) 2015-03-03 US claimed
US-8829206-B2 Production of cyclic acetals or ketals using solid acid catalysts EASTMAN CHEMICAL COMPANY (US) 2014-09-09 US claimed
WO-2012177417-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO claimed
WO-2012177485-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO claimed
WO-2012177469-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO claimed
US-20120330032-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US claimed
US-20120330033-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US claimed
US-20120330069-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US claimed
US-9440944-B2 Production of cyclic acetals or ketals using solid acid catalysts EASTMAN CHEMICAL COMPANY (US) 2016-09-13 US disclosed
US-9394271-B2 Production of cyclic acetals or ketals using liquid-phase acid catalysts EASTMAN CHEMICAL COMPANY (US) 2016-07-19 US disclosed
US-9388105-B2 Production of hydroxy ether hydrocarbons by liquid phase hydrogenolysis of cyclic acetals or cyclic ketals EASTMAN CHEMICAL COMPANY (US) 2016-07-12 US disclosed
US-9382179-B2 Nickel modified catalyst for the production of hydroxy ether hydrocarbons by vapor phase hydrogenolysis of cyclic acetals and ketals EASTMAN CHEMICAL COMPANY (US) 2016-07-05 US disclosed
US-9315485-B2 Production of cyclic acetals by reactive distillation EASTMAN CHEMICAL COMPANY (US) 2016-04-19 US disclosed
WO-2012177417-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO disclosed
WO-2012177591-A1 NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO disclosed
US-20120330068-A1 NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 US disclosed
WO-2012177484-A1 CATALYSTS FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO disclosed
WO-2012177485-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS EASTMAN CHEMICAL COMPANY (US) 2012-12-27 WO disclosed
US-20110184072-A1 FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE PECHERE LAURENT 2011-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110184072-A1 FORMULATION INTENDED TO IMPROVING THE BIOAVAILABILITY OF A HYDROPHOBIC MOLECULE FABP2, SI, SLC10A2 TTR 523/4885CHRM2 3452/4885CHRM4 3012/4885
US-20120330069-A1 PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY LIQUID PHASE HYDROGENOLYSIS OF CYCLIC ACETALS OR CYCLIC KETALS CCNE2, CCNH, HRH2 TTR 4101/4885CHRM2 4613/4885CHRM4 4797/4885
US-20120330068-A1 NICKEL MODIFIED CATALYST FOR THE PRODUCTION OF HYDROXY ETHER HYDROCARBONS BY VAPOR PHASE HYDROGENOLYSIS OF CYCLIC ACETALS AND KETALS KAT5, HRH3, KAT8 TTR 4638/4885CHRM2 4410/4885CHRM4 4327/4885
US-20120330032-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING SOLID ACID CATALYSTS PKLR, AKR1C4, AKR1C2 TTR 4861/4885CHRM2 4632/4885CHRM4 4441/4885
US-20120330033-A1 PRODUCTION OF CYCLIC ACETALS OR KETALS USING LIQUID-PHASE ACID CATALYSTS PKLR, KHK, PHYKPL TTR 4780/4885CHRM2 4374/4885CHRM4 4532/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.