SCHEMBL7204352

SCHEMBL7204352

CC(C)c1ccc(O)cc1-c1ccc(OC#N)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
BACE1 P56817 1/20 0.35
ALDH2 P05091 1/20 0.34
MAOA P21397 1/20 0.34
MAOB P27338 1/20 0.34
ANPEP P15144 1/20 0.34
DPP4 P27487 1/20 0.34
PPARA Q07869 2/20 0.33
PPARG P37231 1/20 0.33
ABL1 P00519 1/20 0.33
ABCB1 P08183 1/20 0.33
BCR P11274 1/20 0.33
ESR2 Q92731 5/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29634663 0.83 HSP90AA1 (0.32) PPARAPPARGMAPTHPGDRXFP1
SCHEMBL9468971 0.82 ANPEP (0.44) MAOAMAOBANPEPDPP4ESR2
SCHEMBL27519877 0.81 ESR1 (0.44) MAOAMAOBANPEPDPP4ABL1
SCHEMBL27486541 0.78 CA12 (0.47) PPARAPPARGABL1ABCB1BCR
SCHEMBL8507355 0.75 ESR2 (0.53) MEN1KMT2ABACE1ABL1ABCB1
SCHEMBL10518876 0.74 APP (0.42) ANPEPDPP4ESR2ESR1
SCHEMBL27541519 0.74 CYP19A1 (0.45) MEN1KMT2AALDH2ESR2NPC1
SCHEMBL3627283 0.73 USP7 (0.32)
SCHEMBL27943145 0.73
SCHEMBL11774210 0.73 ESR2 (0.52) MEN1KMT2AABL1ABCB1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6603035-B1 A method for producing a high purity cyanate comprising reacting a phenol compound represented by the following formula SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-05 US disclosed
US-6225492-B1 CONTACTING CYANATE CRUDE PRODUCT SOLUTION COMPRISING CYANATE, UNSUBSTITUTED PHENOL AND NON-ALCOHOLIC SOLVENT WITH POOR SOLVENT CONTAINING ALCOHOL AND WATER TO CRYSTALLIZE OR PRECIPITATE SAID CYANATE SUMITOMO CHEMICAL CO., LTD. (JP) 2001-05-01 US disclosed