Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 8/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27519877 | 0.98 | ESR1 (0.44) | ANPEPDPP4CA1CA2LMNA | |
| SCHEMBL10518876 | 0.91 | APP (0.42) | ANPEPDPP4CA1CA2LMNA | |
| SCHEMBL16528151 | 0.89 | ANPEP (0.47) | ANPEPDPP4CA1CA2LMNA | |
| SCHEMBL28000746 | 0.84 | TRPA1 (0.55) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL671994 | 0.84 | TRPA1 (0.46) | CA1CA2LMNASLC6A2HTR2B | |
| SCHEMBL9034484 | 0.83 | USP7 (0.43) | ANPEPCA1CA2LMNASLC6A2 | |
| SCHEMBL29539720 | 0.83 | USP7 (0.45) | CA1CA2LMNASLC6A2HTR2B | |
| SCHEMBL7204352 | 0.82 | MEN1 (0.35) | ANPEPDPP4ESR1ESR2MAOA | |
| SCHEMBL4196046 | 0.81 | HSD17B10 (0.46) | ANPEPDPP4CA1CA2ESR1 | |
| SCHEMBL31544912 | 0.81 | TYR (0.47) | ANPEPDPP4LMNASLC6A2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264538-A | Cyclic poly(aryl ether) oligomers | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| US-5264520-A | Polymerization of cyclic poly(aryl ether) oligomers | THE DOW CHEMICAL COMPANY (US) | 1993-11-23 | — | — | US | disclosed |
| EP-0413257-A2 | Cyclic poly(aryl ether) oligomers, a process for preparation thereof, and polymerization of cyclic poly (aryl ether) oligomers | THE DOW CHEMICAL COMPANY (US) | 1991-02-20 | — | — | EP | disclosed |