Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.45 |
| ▸ | TMIGD3 | P0DMS9 | 6/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205691 | 0.90 | ADORA2A (0.45) | ADORA2AADORA2BADORA1TMIGD3ADORA3 | |
| SCHEMBL7205552 | 0.87 | ADORA2A (0.58) | ADORA2AADORA2BADORA1TMIGD3ADORA3 | |
| SCHEMBL7206459 | 0.84 | TMIGD3 (0.54) | ADORA2AADORA2BADORA1TMIGD3TLR7 | |
| SCHEMBL7206499 | 0.83 | TLR7 (0.47) | ADORA2AADORA2BADORA1TMIGD3TLR7 | |
| SCHEMBL7209368 | 0.83 | TMIGD3 (0.48) | ADORA2AADORA2BADORA1TMIGD3TLR7 | |
| SCHEMBL7208663 | 0.82 | TMIGD3 (0.57) | ADORA2AADORA2BADORA1TMIGD3TLR7 | |
| SCHEMBL7211508 | 0.81 | ADORA2A (0.59) | ADORA2AADORA2BADORA1TMIGD3ADORA3 | |
| SCHEMBL7209428 | 0.81 | ADORA2A (0.48) | ADORA2AADORA2BADORA1TMIGD3ADORA3 | |
| SCHEMBL7206373 | 0.80 | L3MBTL1 (0.47) | ADORA2AADORA2BADORA1TMIGD3ADORA3 | |
| SCHEMBL4474934 | 0.80 | TLR7 (0.62) | ADORA2AADORA2BADORA1TMIGD3TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |