Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ADK | P55263 | 15/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206447 | 0.86 | LMNA (0.49) | LMNAADKSMN1; SMN2 | |
| SCHEMBL7209492 | 0.86 | LMNA (0.55) | LMNAADK | |
| SCHEMBL8184942 | 0.86 | LMNA (0.55) | LMNAADK | |
| SCHEMBL8192386 | 0.86 | LMNA (0.49) | LMNAADKSMN1; SMN2 | |
| SCHEMBL7211564 | 0.86 | LMNA (0.37) | LMNAADKSMN1; SMN2 | |
| SCHEMBL2368990 | 0.85 | LMNA (0.64) | LMNAADKSMN1; SMN2 | |
| SCHEMBL2368996 | 0.85 | LMNA (0.64) | LMNAADKSMN1; SMN2 | |
| SCHEMBL7208745 | 0.84 | LMNA (0.55) | LMNAADK | |
| SCHEMBL8184925 | 0.84 | LMNA (0.55) | LMNAADK | |
| SCHEMBL3820232 | 0.84 | LMNA (0.54) | LMNAADKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | claimed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | claimed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | claimed |
| EP-1060183-B1 | 5'-DEOXYCYTIDINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1060183-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999040099-A1 | 5'-DEOXYCYTIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-08-12 | — | — | WO | disclosed |