Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ADH1B | P00325 | 2/20 | 0.42 |
| ▸ | ADH1C | P00326 | 2/20 | 0.42 |
| ▸ | ADH1A | P07327 | 2/20 | 0.42 |
| ▸ | ADH4 | P08319 | 2/20 | 0.42 |
| ▸ | ADH7 | P40394 | 2/20 | 0.42 |
| ▸ | FDPS | P14324 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | GAPDH | P04406 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7209541 | 1.00 | LMNA (0.45) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL7205361 | 1.00 | LMNA (0.45) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL18400778 | 1.00 | LMNA (0.45) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL18613557 | 0.98 | LMNA (0.43) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL8634231 | 0.98 | LMNA (0.41) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL27781256 | 0.96 | LMNA (0.42) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL2431569 | 0.94 | LMNA (0.39) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL22627187 | 0.93 | TSHR (0.57) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL1110041 | 0.92 | CYP3A4 (0.47) | LMNATSHRADH1BADH1CADH1A | |
| SCHEMBL2991464 | 0.92 | CYP3A4 (0.47) | LMNATSHRADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903350-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-0518238-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0903350-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5508421-A | Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5362882-A | Intermediates for dyes for polyesters, images for heat sensitive elements and electrography | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0518238-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |