Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 9/20 | 0.51 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27579928 | 0.91 | LSS (0.62) | LSSACHEPTGESMAPTSMN1; SMN2 | |
| SCHEMBL7202898 | 0.79 | LSS (0.69) | LSSACHEPTGESMAPTSMN1; SMN2 | |
| SCHEMBL5015820 | 0.79 | LSS (0.66) | LSSACHE | |
| SCHEMBL5015818 | 0.79 | LSS (0.66) | LSSACHE | |
| SCHEMBL6019239 | 0.76 | LSS (0.46) | LSSACHEPTGESPOLBMAPT | |
| SCHEMBL6019234 | 0.76 | LSS (0.46) | LSSACHEPTGESPOLBMAPT | |
| SCHEMBL6018938 | 0.76 | LSS (0.42) | LSSKMT2A | |
| SCHEMBL6018943 | 0.76 | LSS (0.42) | LSSKMT2A | |
| SCHEMBL7203316 | 0.75 | LSS (0.45) | LSSPOLBMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4808060 | 0.74 | LSS (0.69) | LSSACHEMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |