Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 17/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.57 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | PI4KA | P42356 | 1/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211348 | 0.96 | TLR7 (0.60) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7205144 | 0.94 | PDE4A (0.58) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4133313 | 0.93 | TLR7 (0.57) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7212572 | 0.90 | PDE4A (0.54) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7210234 | 0.89 | PDE4A (0.60) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7211099 | 0.88 | PDE4A (0.55) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2060324 | 0.88 | TLR7 (0.51) | TLR7ADORA2A | |
| SCHEMBL7204698 | 0.88 | PDE4A (0.57) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL509407 | 0.88 | TLR7 (0.64) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL22347140 | 0.87 | TLR7 (0.50) | TLR7ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |