Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.40 |
| ▸ | ODC1 | P11926 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7694918 | 0.87 | HDAC6 (0.49) | LMNAKMT2AMEN1ALOX15RECQL | |
| SCHEMBL7690006 | 0.82 | HDAC6 (0.49) | LMNAKMT2AMEN1ALOX15RECQL | |
| SCHEMBL2115160 | 0.78 | ODC1 (0.48) | FDPSODC1NFKB1CYP2D6BLM | |
| SCHEMBL7444135 | 0.77 | LMNA (0.46) | NFKB1CYP2D6BLMLMNANPSR1 | |
| SCHEMBL9617305 | 0.76 | PAOX (0.44) | FDPSODC1NFKB1CYP2D6BLM | |
| SCHEMBL28869340 | 0.76 | ODC1 (0.47) | FDPSODC1NFKB1CYP2D6BLM | |
| SCHEMBL449961 | 0.74 | PAOX (0.48) | FDPSODC1NFKB1CYP2D6BLM | |
| SCHEMBL8749600 | 0.74 | FAAH (0.48) | FDPSKMT2AMEN1ALDH1A1CYP1A2 | |
| SCHEMBL4278877 | 0.74 | ODC1 (0.46) | FDPSODC1NFKB1CYP2D6BLM | |
| SCHEMBL7202891 | 0.73 | HDAC6 (0.60) | LMNATHRBKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912584-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003519-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |