SCHEMBL7204997

SCHEMBL7204997

C=C(Cc1cccc(-c2ccccc2-c2cccc(CC(=C)C(=O)O)c2)c1)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G10 O15496 1/20 0.45
PLA2G2A P14555 1/20 0.45
SELL P14151 3/20 0.44
SELP P16109 3/20 0.44
SELE P16581 2/20 0.44
PTGER1 P34995 3/20 0.43
PTGER4 P35408 2/20 0.42
PTGER3 P43115 2/20 0.42
PTGER2 P43116 2/20 0.42
SHMT1 P34896 1/20 0.40
SHMT2 P34897 1/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
FAAH O00519 1/20 0.40
NAAA Q02083 1/20 0.40
MAPK1 P28482 1/20 0.39
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5487173 0.90 FAAH (0.48) FAAHNAAAGRIN2DGRIN3BGRIN1
SCHEMBL3423556 0.84 CTBP2 (0.44)
SCHEMBL17187933 0.82 PLA2G10 (0.60) PLA2G10PLA2G2ASELLSELPSELE
SCHEMBL3839813 0.81 PLA2G10 (0.58) PLA2G10PLA2G2ASELLSELPSELE
SCHEMBL41907 0.80 CES1 (0.58) MAPK1
SCHEMBL27976611 0.80 APP (0.50) SHMT1SHMT2GRIN2DGRIN3BGRIN1
SCHEMBL27564061 0.78 CES1 (0.56) MAPK1
Hydrochloric Acid SCHEMBL27862997 0.78 CES1 (0.56) MAPK1
Bromide SCHEMBL11497452 0.78 CES1 (0.56) MAPK1
SCHEMBL1137221 0.77 CTBP2 (0.60) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0643318-B1 DISPLAY DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORP (JP) 2003-01-02 EP disclosed
US-5993689-A Polymer dispersed liquid crystal (PDLC) display element for use in an electronic apparatus SEIKO EPSON CORPORATION (JP) 1999-11-30 US disclosed
US-5686017-A Polymer dispersed liquid crystal (PDLC) display element for use in an electronic apparatus SEIKO EPSON CORPORATION (JP) 1997-11-11 US disclosed
EP-0643318-A1 DISPLAY DEVICE AND ELECTRONIC APPARATUS SEIKO EPSON CORPORATION (JP) 1995-03-15 EP disclosed