Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867761 | 0.74 | MAPK1 (0.48) | MAPTHSD17B10TSHRTDP1KDM4E | |
| SCHEMBL22140656 | 0.67 | POLB (0.60) | MAPTHPGDHSD17B10ALOX15APP | |
| SCHEMBL25468883 | 0.67 | MAOA (0.57) | MAPTHPGDHSD17B10ALOX15APP | |
| SCHEMBL8835986 | 0.67 | MAPT (0.52) | MAPTHPGDHSD17B10ALOX15APP | |
| SCHEMBL30342267 | 0.67 | MAOA (0.57) | MAPTHPGDHSD17B10ALOX15APP | |
| SCHEMBL6254791 | 0.67 | MAPT (0.52) | MAPTHPGDHSD17B10ALOX15APP | |
| SCHEMBL22140657 | 0.66 | MAPT (0.59) | MAPTHPGDHSD17B10ALOX15APP | |
| SCHEMBL1683948 | 0.64 | HPGD (0.62) | MAPTHPGDHSD17B10ALOX15APP | |
| SCHEMBL2407577 | 0.64 | HPGD (1.00) | MAPTHPGDHSD17B10ALOX15APP | |
| SCHEMBL31229389 | 0.64 | HPGD (0.62) | MAPTHPGDHSD17B10ALOX15APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602679-B2 | Substrate of an oxidant, stabilizer and buffer with an extended shelf life is useful with enzyme based probes; detecting DNA fragments in DNA sequencing | GIRI BRIJ (US) | 2003-08-05 | — | — | US | disclosed |
| US-20010046688-A1 | Novel stabilized formulations for chemiluminescent assays | GIRI BRIJ PAL (US) | 2001-11-29 | — | — | US | disclosed |