Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | LSS | P48449 | 5/20 | 0.42 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205073 | 1.00 | ALDH1A1 (0.46) | ALDH1A1LMNAPTBP1LSSCCKBR | |
| SCHEMBL7209755 | 0.90 | LSS (0.48) | LSSATMRAB9ANPY5RKMT2A | |
| SCHEMBL7206024 | 0.90 | LSS (0.48) | LSSATMRAB9ANPY5RKMT2A | |
| SCHEMBL7211608 | 0.90 | FPR3 (0.42) | LSSATMRAB9ANPY5RKMT2A | |
| SCHEMBL7209436 | 0.90 | FPR3 (0.42) | LSSATMRAB9ANPY5RKMT2A | |
| SCHEMBL7208575 | 0.90 | LSS (0.48) | LSSATMRAB9ANPY5RKMT2A | |
| SCHEMBL7208569 | 0.90 | LSS (0.48) | LSSATMRAB9ANPY5RKMT2A | |
| SCHEMBL7209439 | 0.90 | FPR3 (0.42) | LSSATMRAB9ANPY5RKMT2A | |
| SCHEMBL7205235 | 0.90 | FPR3 (0.42) | LSSATMRAB9ANPY5RKMT2A | |
| SCHEMBL7209758 | 0.90 | LSS (0.48) | LSSATMRAB9ANPY5RKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |