Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRA | P18433 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075846 | 0.90 | PTPRA (0.51) | PTPRACYP1A2SMN1; SMN2CYP2C19HRH1 | |
| SCHEMBL1857456 | 0.89 | GRIK1 (0.54) | PTPRACYP1A2SMN1; SMN2CYP2C19RAB9A | |
| SCHEMBL8868140 | 0.88 | SMN1; SMN2 (0.50) | PTPRACYP1A2SMN1; SMN2CYP2C19HRH1 | |
| SCHEMBL7075416 | 0.87 | PTPRA (0.59) | PTPRACYP1A2SMN1; SMN2CYP2C19HRH1 | |
| SCHEMBL1176394 | 0.83 | SLC1A5 (0.56) | PTPRACYP1A2SMN1; SMN2CYP2C19HRH1 | |
| SCHEMBL30428132 | 0.83 | SLC1A5 (0.56) | PTPRACYP1A2SMN1; SMN2CYP2C19HRH1 | |
| SCHEMBL1768948 | 0.83 | SLC1A5 (0.56) | PTPRACYP1A2SMN1; SMN2CYP2C19HRH1 | |
| SCHEMBL1130371 | 0.83 | PTPRA (0.54) | PTPRACYP1A2SMN1; SMN2CYP2C19HRH1 | |
| SCHEMBL10367159 | 0.81 | PTPRA (0.53) | PTPRACYP1A2SMN1; SMN2CYP2C19HRH1 | |
| SCHEMBL7613692 | 0.81 | MMP3 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882712-B1 | PROCESS FOR PREPARING ACID SALTS OF GAMMA-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO (JP) | 2003-04-23 | — | — | EP | claimed |
| US-6197961-B1 | HYDROGENATION OF G-(PYRIDYL)BUTYRIC ACID SALT IN SOLVENT USING PALLADIUM, RHODIUM, OR RUTHENIUM CATALYST; HYDROLYSIS, DECARBOXYLATION | KOEI CHEMICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | claimed |
| EP-0882712-A1 | PROCESS FOR PREPARING ACID SALTS OF $g(g)-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | claimed |
| EP-0882712-B1 | PROCESS FOR PREPARING ACID SALTS OF GAMMA-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| EP-0882712-B1 | PROCESS FOR PREPARING ACID SALTS OF GAMMA-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6197961-B1 | HYDROGENATION OF G-(PYRIDYL)BUTYRIC ACID SALT IN SOLVENT USING PALLADIUM, RHODIUM, OR RUTHENIUM CATALYST; HYDROLYSIS, DECARBOXYLATION | KOEI CHEMICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| US-6197961-B1 | HYDROGENATION OF G-(PYRIDYL)BUTYRIC ACID SALT IN SOLVENT USING PALLADIUM, RHODIUM, OR RUTHENIUM CATALYST; HYDROLYSIS, DECARBOXYLATION | KOEI CHEMICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0882712-A4 | PROCESS FOR PREPARING ACID SALTS OF -g(g)-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO (JP) | 1999-12-08 | — | — | EP | disclosed |
| EP-0882712-A1 | PROCESS FOR PREPARING ACID SALTS OF $g(g)-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |
| EP-0882712-A1 | PROCESS FOR PREPARING ACID SALTS OF $g(g)-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO., LTD. (JP) | 1998-12-09 | — | — | EP | disclosed |
| WO-1998015531-A1 | PROCESS FOR PREPARING ACID SALTS OF η-(PIPERIDYL)BUTYRIC ACID | KOEI CHEMICAL CO., LTD. (JP) | 1998-04-16 | — | — | WO | disclosed |