Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1088319 | 0.81 | SPHK1 (0.42) | SPHK1CTSK | |
| SCHEMBL29060117 | 0.80 | SPHK1 (0.33) | SPHK1CTSK | |
| SCHEMBL15418773 | 0.80 | TDP1 (0.43) | SPHK1CTSK | |
| SCHEMBL1088614 | 0.80 | SPHK1 (0.47) | SPHK1 | |
| Iodide SCHEMBL7205249 | 0.79 | — | — | |
| SCHEMBL1100128 | 0.79 | SPHK1 (0.49) | SPHK1 | |
| SCHEMBL7205303 | 0.79 | SPHK1 (0.33) | SPHK1CTSK | |
| SCHEMBL15418650 | 0.77 | CTSK (0.36) | SPHK1CTSK | |
| SCHEMBL1089166 | 0.77 | SPHK1 (0.35) | SPHK1CTSK | |
| SCHEMBL9604817 | 0.76 | CTSK (0.33) | CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1144783-C | prostaglandin derivatives | ������ҩ��ʽ���� | 2004-04-07 | — | — | CN | disclosed |
| EP-1083168-B1 | PROSTAGLANDIN DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2003-10-22 | — | — | EP | disclosed |
| US-6329539-B1 | Prostagladin derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-12-11 | — | — | US | disclosed |
| CN-1303370-A | prostaglandin derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2001-07-11 | — | — | CN | disclosed |
| EP-1083168-A1 | PROSTAGLANDIN DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2001-03-14 | — | — | EP | disclosed |