Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29060117 | 0.89 | SPHK1 (0.33) | CTSK | |
| SCHEMBL1089166 | 0.82 | SPHK1 (0.35) | CTSK | |
| SCHEMBL27546342 | 0.80 | CTSK (0.33) | CTSK | |
| SCHEMBL13926370 | 0.78 | DGAT1 (0.32) | CTSK | |
| SCHEMBL1088319 | 0.78 | SPHK1 (0.42) | CTSK | |
| SCHEMBL15418773 | 0.77 | TDP1 (0.43) | CTSK | |
| SCHEMBL1088806 | 0.77 | CTSK (0.35) | CTSK | |
| SCHEMBL27014757 | 0.77 | CTSK (0.35) | CTSK | |
| Iodide SCHEMBL7205304 | 0.76 | SPHK1 (0.33) | CTSK | |
| SCHEMBL1100128 | 0.76 | SPHK1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120135980-A1 | GAMMA SECRETASE MODULATORS | SCHERING CORPORATION | 2012-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120135980-A1 | GAMMA SECRETASE MODULATORS | BACE1, BACE2, GSAP | CTSK 140/4885FAAH 342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.