Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.55 |
| ▸ | MMP8 | P22894 | 2/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.52 |
| ▸ | F13A1 | P00488 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 7/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205323 | 1.00 | MMP9 (0.55) | MMP9MMP8MMP14CAPN1F13A1 | |
| SCHEMBL14513403 | 0.93 | MMP9 (0.63) | MMP9MMP8MMP14CAPN1PYGL | |
| SCHEMBL5587642 | 0.93 | MMP9 (0.63) | MMP9MMP8MMP14CAPN1PYGL | |
| SCHEMBL7202948 | 0.92 | MMP9 (0.50) | MMP9MMP8MMP14CAPN1F13A1 | |
| SCHEMBL7205260 | 0.92 | MMP9 (0.50) | MMP9MMP8MMP14CAPN1F13A1 | |
| SCHEMBL7205257 | 0.92 | MMP9 (0.50) | MMP9MMP8MMP14CAPN1F13A1 | |
| SCHEMBL7202940 | 0.92 | MMP9 (0.50) | MMP9MMP8MMP14CAPN1F13A1 | |
| Hydrochloric Acid SCHEMBL7208321 | 0.90 | MMP9 (0.48) | MMP9MMP8MMP14CAPN1F13A1 | |
| SCHEMBL7203445 | 0.90 | MMP9 (0.48) | MMP9MMP8MMP14CAPN1F13A1 | |
| SCHEMBL7203452 | 0.90 | MMP9 (0.48) | MMP9MMP8MMP14CAPN1F13A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921122-B1 | EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-6110967-A | USEFUL AS AGENTS FOR PREVENTING AND TREATING METABOLIC OSTEOPATHY SUCH AS OSTEOPOROSIS, HYPERCALCEMIA AND BONE METASTASIS OF CANCER BECAUSE THEY SPECIFICALLY INHIBITS CATHEPSIN L AND ITS FAMILY ENZYMES TO INHIBIT BONE RESORPTION | TAIHO PHARMACEUTICALS CO., LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0921122-A1 | NOVEL EPOXYSUCCINAMIDE DERIVATIVES OR SALTS THEREOF | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1999-06-09 | — | — | EP | disclosed |