Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349828 | 0.79 | GABRR1 (0.40) | GABRR1GLRA1SLC6A9OR51E2 | |
| SCHEMBL349827 | 0.79 | GLRA1 (0.45) | GABRR1GLRA1SLC6A9OR51E2 | |
| SCHEMBL28318302 | 0.70 | KDM4E (0.33) | GABRR1 | |
| SCHEMBL19267502 | 0.67 | — | — | |
| SCHEMBL1226620 | 0.65 | — | — | |
| Water SCHEMBL4998322 | 0.65 | GABRR1 (0.36) | GABRR1GLRA1SLC6A9OR51E2 | |
| SCHEMBL7205332 | 0.63 | GLRA1 (0.37) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL9642490 | 0.63 | — | — | |
| SCHEMBL11097500 | 0.62 | ODC1 (0.53) | GABRR1GLRA1SLC6A9OR51E2 | |
| SCHEMBL11097504 | 0.62 | ODC1 (0.53) | GABRR1GLRA1SLC6A9OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912584-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003519-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |