Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.37 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349825 | 0.86 | GLRA1 (0.38) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL11027538 | 0.78 | MGAM (0.35) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL16053163 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL11235353 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL6535201 | 0.77 | TDP1 (0.33) | — | |
| SCHEMBL9219012 | 0.71 | OR51E2 (0.32) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL825611 | 0.71 | SMN1; SMN2 (0.42) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL3185113 | 0.71 | THRB (0.43) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL7204897 | 0.71 | FDPS (0.40) | — | |
| SCHEMBL4361740 | 0.71 | MEN1 (0.39) | GLRA1SLC6A9OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912584-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003519-A2 | NEW BIS-PLATINUM COMPLEXES WITH POLYAMINE LIGANDS AS ANTITUMOR AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-01-29 | — | — | WO | disclosed |