Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205670 | 0.91 | MEN1 (0.39) | SMN1; SMN2ALDH1A1HTR2ALMNACYP19A1 | |
| SCHEMBL24992 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HTR2ALMNAHTT | |
| SCHEMBL2235530 | 0.73 | HTR2A (0.54) | SMN1; SMN2ALDH1A1HTR2ALMNAHTT | |
| SCHEMBL28216680 | 0.72 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1LMNAHTTTDP1 | |
| SCHEMBL5492543 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNAHTTTDP1 | |
| SCHEMBL24993 | 0.72 | MEN1 (0.40) | SMN1; SMN2ALDH1A1LMNATDP1MEN1 | |
| SCHEMBL636942 | 0.72 | MEN1 (0.40) | SMN1; SMN2ALDH1A1LMNATDP1MEN1 | |
| SCHEMBL27590312 | 0.71 | HSD17B10 (0.49) | SMN1; SMN2ALDH1A1LMNAHTTPKM | |
| SCHEMBL27590300 | 0.71 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1LMNACYP19A1HTT | |
| SCHEMBL5147270 | 0.71 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNAHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158089-A1 | Administrative agents via the SMVT transporter | XENOPORT, INC. | 2003-08-21 | — | — | US | disclosed |