Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205668 | 0.91 | SMN1; SMN2 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL636942 | 0.81 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL24993 | 0.81 | MEN1 (0.40) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3639263 | 0.79 | HTT (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL27164 | 0.79 | LMNA (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1249807 | 0.77 | HTT (0.58) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7200631 | 0.76 | KMT2A (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7200623 | 0.76 | KMT2A (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3067746 | 0.75 | MAPT (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3067750 | 0.75 | MAPT (0.43) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158089-A1 | Administrative agents via the SMVT transporter | XENOPORT, INC. | 2003-08-21 | — | — | US | disclosed |