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SCHEMBL7205709

SCHEMBL7205709

CCC(=O)NCCCOC(=O)Nc1nc(=O)n([C@@H]2O[C@H](C)[C@@H](OC(C)=O)[C@H]2OC(C)=O)cc1I

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.47
▸ ADK P55263 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8192678 1.00 LMNA (0.47) LMNAADK
SCHEMBL7204782 0.93 LMNA (0.47) LMNAADK
SCHEMBL8196905 0.93 LMNA (0.47) LMNAADK
SCHEMBL3821749 0.90 LMNA (0.56) LMNAADK
SCHEMBL3821461 0.89 LMNA (0.59) LMNAADK
SCHEMBL3817191 0.88 LMNA (0.51) LMNAADK
SCHEMBL7205814 0.88 LMNA (0.49) LMNAADK
SCHEMBL8193927 0.88 LMNA (0.49) LMNAADK
SCHEMBL8193747 0.88 LMNA (0.49) LMNAADK
SCHEMBL7209654 0.88 LMNA (0.49) LMNAADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1060183-B1 5'-DEOXYCYTIDINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2003-04-23 — — EP disclosed