Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 9/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28975617 | 0.85 | SIGMAR1 (0.47) | SIGMAR1GAAKDM4ENCEH1ALDH1A1 | |
| SCHEMBL7110585 | 0.83 | SIGMAR1 (0.45) | SIGMAR1GAAKDM4EALOX5L3MBTL1 | |
| SCHEMBL27532540 | 0.78 | GAA (0.44) | SIGMAR1GAAKDM4EALOX5F2 | |
| SCHEMBL1839015 | 0.77 | SIGMAR1 (0.65) | SIGMAR1GAAKDM4EALOX5NCEH1 | |
| SCHEMBL7314114 | 0.77 | DHODH (0.42) | SIGMAR1MEN1KMT2AHSD17B10NR4A1 | |
| SCHEMBL9547530 | 0.77 | SIGMAR1 (0.51) | SIGMAR1GAAKDM4EALOX5ALDH1A1 | |
| SCHEMBL6685262 | 0.77 | SIGMAR1 (0.48) | SIGMAR1GAAKDM4EALOX5ALDH1A1 | |
| SCHEMBL5320236 | 0.75 | SIGMAR1 (0.47) | SIGMAR1GAAKDM4EALOX5ALDH1A1 | |
| SCHEMBL3294924 | 0.75 | SIGMAR1 (0.47) | SIGMAR1GAAKDM4EALOX5MEN1 | |
| SCHEMBL28754971 | 0.75 | SIGMAR1 (0.47) | SIGMAR1GAAKDM4EALOX5NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003068223-A1 | ARYL UREAS WITH RAF KINASE AND ANGIOGENESIS INHIBITING ACTIVITY | BAYER CORPORATION (US) | 2003-08-21 | — | — | WO | disclosed |