Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25C | P30307 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206012 | 0.83 | SIGMAR1 (0.46) | SIGMAR1ALDH1A1KDM4EGAAALOX5 | |
| SCHEMBL27515197 | 0.76 | SIGMAR1 (0.62) | SIGMAR1TSHRALDH1A1KDM4ELMNA | |
| SCHEMBL5510643 | 0.74 | ALDH1A1 (0.44) | TSHRALDH1A1HPGDLMNANPSR1 | |
| SCHEMBL1839015 | 0.74 | SIGMAR1 (0.65) | SIGMAR1KDM4EGAAALOX5 | |
| SCHEMBL9547530 | 0.73 | SIGMAR1 (0.51) | SIGMAR1TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL6685262 | 0.73 | SIGMAR1 (0.48) | SIGMAR1TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL27586726 | 0.73 | SIGMAR1 (0.45) | SIGMAR1TSHRALDH1A1HPGDKDM4E | |
| SCHEMBL31558690 | 0.72 | ALDH1A1 (0.52) | TSHRALDH1A1HPGDCDC25BKDM4E | |
| SCHEMBL3138343 | 0.72 | SIGMAR1 (0.45) | SIGMAR1TSHRALDH1A1HPGDCDC25B | |
| SCHEMBL27713672 | 0.72 | SIGMAR1 (0.41) | SIGMAR1TSHRALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130309-A1 | Methods of treating cytokine mediated diseases | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-07-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130309-A1 | Methods of treating cytokine mediated diseases | IL2, IFNG, IL1A | SIGMAR1 3047/4885TSHR 1924/4885ALDH1A1 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.