Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206324 | 1.00 | ADORA3 (0.49) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7207888 | 0.91 | ADORA2A (0.49) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7203070 | 0.88 | ADORA3 (0.53) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL8100503 | 0.88 | ADORA3 (0.53) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7208447 | 0.88 | ADORA2A (0.47) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7205590 | 0.87 | PGK1 (0.58) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7205046 | 0.87 | PGK1 (0.45) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7206736 | 0.85 | ADORA2A (0.59) | ADORA3ADORA2AADORA2BADORA1 | |
| Trifluoroacetic Acid SCHEMBL7210128 | 0.85 | ADORA2A (0.49) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL7205090 | 0.85 | ADORA2A (0.52) | ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610665-B1 | Treatment of inflammatory diseases, asthma or chronic obstructive pulmonary disease | SMITHKLINE BEECHAM CORPORATION | 2003-08-26 | — | — | US | disclosed |