SCHEMBL7206410

SCHEMBL7206410

O=C(CC(=O)c1cccs1)c1ccc(F)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 2/20 0.56
ERCC5 P28715 1/20 0.56
FEN1 P39748 1/20 0.56
POLB P06746 2/20 0.55
MEN1 O00255 6/20 0.55
KMT2A Q03164 6/20 0.55
LMNA P02545 4/20 0.55
NPC1 O15118 4/20 0.55
RAB9A P51151 3/20 0.55
ALDH1A1 P00352 3/20 0.55
MAPT P10636 5/20 0.53
SMN1; SMN2 Q16637 4/20 0.53
HPGD P15428 3/20 0.53
GSK3B P49841 1/20 0.51
HTT P42858 2/20 0.51
ALOX12 P18054 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
MAPK1 P28482 1/20 0.51
GAA P10253 2/20 0.49
CRHBP P24387 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28816497 0.98 CTNNB1 (0.55) CTNNB1ERCC5FEN1POLBMEN1
SCHEMBL7205526 0.95 CTNNB1 (0.52) CTNNB1ERCC5FEN1POLBMEN1
SCHEMBL15988694 0.87 POLB (0.70) CTNNB1POLBMEN1KMT2ALMNA
SCHEMBL7200952 0.85 MEN1 (0.58) CTNNB1ERCC5FEN1POLBMEN1
SCHEMBL1436183 0.84 ERCC5 (0.66) CTNNB1ERCC5FEN1POLBMEN1
SCHEMBL7204970 0.84 PTPN1 (0.55) CTNNB1ERCC5FEN1POLBMEN1
SCHEMBL711360 0.84 RAB9A (0.75) CTNNB1ERCC5FEN1POLBMEN1
SCHEMBL7202020 0.83 CTNNB1 (0.56) CTNNB1ERCC5FEN1POLBMEN1
SCHEMBL7200564 0.83 RAB9A (0.67) CTNNB1ERCC5FEN1POLBMEN1
SCHEMBL7202370 0.83 CTNNB1 (0.56) CTNNB1ERCC5FEN1POLBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170271712-A1 POSITIVE ELECTRODE ACTIVE MATERIAL FOR A LITHIUM ION SECONDARY BATTERY, METHOD FOR MANUFACTURING THE SAME, AND LITHIUM ION SECONDARY BATTERY NEC CORPORATION (JP) 2017-09-21 US disclosed
US-20170271712-A1 POSITIVE ELECTRODE ACTIVE MATERIAL FOR A LITHIUM ION SECONDARY BATTERY, METHOD FOR MANUFACTURING THE SAME, AND LITHIUM ION SECONDARY BATTERY NEC CORPORATION (JP) 2017-09-21 US disclosed
CN-103237865-B Spherical phosphor, sealing material for wavelength conversion type solar cell, solar cell module, and methods for producing same 日立化成株式会社 2016-08-24 CN disclosed
CN-103384920-B Wavelength conversion type solar cell sealing material and solar cell module HITACHI CHEMICAL CO.,LTD. (JP) 2016-02-17 CN disclosed
CN-104485371-A Spherical phosphor, sealing material for wavelength-conversion-type solar batteries, solar battery module, and process for manufacture of those HITACHI CHEMICAL CO LTD 2015-04-01 CN disclosed
US-8860165-B2 Wavelength conversion-type photovoltaic cell sealing material and photovoltaic cell module using the same HITACHI CHEMICAL COMPANY, LTD. (JP) 2014-10-14 US disclosed
US-20130328149-A1 WAVELENGTH CONVERSION-TYPE PHOTOVOLTAIC CELL SEALING MATERIAL AND PHOTOVOLTAIC CELL MODULE USING THE SAME HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-12-12 US disclosed
CN-103384920-A Wavelength conversion type solar cell sealing material and solar cell module using same HITACHI CHEMICAL CO LTD 2013-11-06 CN disclosed
EP-2650342-A1 SPHERICAL PHOSPHOR, SEALING MATERIAL FOR WAVELENGTH-CONVERSION-TYPE SOLAR BATTERIES, SOLAR BATTERY MODULE, AND PROCESS FOR MANUFACTURE OF THOSE Hitachi Chemical Company, Ltd. (JP) 2013-10-16 EP disclosed
US-20130255778-A1 SPHERICAL PHOSPHOR, WAVELENGTH CONVERSION-TYPE PHOTOVOLTAIC CELL SEALING MATERIAL, PHOTOVOLTAIC CELL MODULE, AND PRODUCTION METHODS THEREOF HITACHI CHEMICAL COMPANY, LTD. 2013-10-03 US disclosed
US-20130231468-A1 RARE EARTH METAL COMPLEX HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-09-05 US disclosed
US-20130231468-A1 RARE EARTH METAL COMPLEX HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-09-05 US disclosed
US-20130231468-A1 RARE EARTH METAL COMPLEX HITACHI CHEMICAL COMPANY, LTD. (JP) 2013-09-05 US disclosed
CN-103237865-A Spherical phosphor, sealing material for wavelength conversion type solar cell, solar cell module, and methods for producing same HITACHI CHEMICAL CO LTD 2013-08-07 CN disclosed
CN-103228641-A Rare earth metal complex HITACHI CHEMICAL CO LTD 2013-07-31 CN disclosed
US-6605730-B2 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula NIHON BAYER AGROCHEM K.K. (JP) 2003-08-12 US disclosed
US-20030028034-A1 Nematicidal pyrazoles WADA KATSUAKI (JP) 2003-02-06 US disclosed
US-6310049-B1 3-(2-THIENYL),5-(SUBSTITUTED PHENYL)-1H-PYRAZOLES AND 3-(SUBSTITUTED PHENYL),5-(2-THIENYL)-1H-PYRAZOLES OF GIVEN FORMULA; ANTHELMINTICS NIHON BAYER AGROCHEM K.K. (JP) 2001-10-30 US disclosed
EP-1104418-A2 NEMATICIDAL PYRAZOLES NIHON BAYER AGROCHEM K.K. (JP) 2001-06-06 EP disclosed
WO-2000009500-A2 NEMATICIDAL PYRAZOLES NIHON BAYER AGROCHEM K.K. (JP) 2000-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030028034-A1 Nematicidal pyrazoles CBR3, CBR1, CCR4 CTNNB1 2248/4885ERCC5 2903/4885FEN1 3825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.