SCHEMBL1436183

SCHEMBL1436183

O=C(CC(=O)c1cccs1)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ERCC5 P28715 1/20 0.66
▸ FEN1 P39748 1/20 0.66
▸ RAB9A P51151 6/20 0.64
▸ HPGD P15428 6/20 0.63
▸ KMT2A Q03164 5/20 0.63
▸ MEN1 O00255 4/20 0.63
▸ CYP3A4 P08684 2/20 0.63
▸ MAPT P10636 2/20 0.63
▸ SMN1; SMN2 Q16637 2/20 0.63
▸ KDM4E B2RXH2 1/20 0.63
▸ ALOX15 P16050 1/20 0.63
▸ CES1 P23141 1/20 0.63
▸ MAPK1 P28482 1/20 0.63
▸ TDP1 Q9NUW8 1/20 0.63
▸ HPGDS O60760 1/20 0.61
▸ ALDH1A1 P00352 6/20 0.61
▸ NPC1 O15118 5/20 0.61
▸ LMNA P02545 2/20 0.61
▸ NFKB1 P19838 1/20 0.61
▸ NFKB2 Q00653 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28972877 0.93 HPGDS (0.59) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL7205003 0.90 ERCC5 (0.58) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL711360 0.88 RAB9A (0.75) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL7200952 0.86 MEN1 (0.58) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL15979661 0.85 ALDH1A1 (0.78) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL7202370 0.84 CTNNB1 (0.56) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL7202020 0.84 CTNNB1 (0.56) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL7206410 0.84 CTNNB1 (0.56) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL7200564 0.84 RAB9A (0.67) ERCC5FEN1RAB9AHPGDKMT2A
SCHEMBL7207262 0.84 NPC1 (0.67) ERCC5FEN1RAB9AHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111479628-B Moisture-curable composition 科思创德国股份有限公司 2024-03-08 — — CN claimed
US-11834545-B2 Moisture-curing compositions COVESTRO DEUTSCHLAND AG (DE) 2023-12-05 — — US claimed
EP-3727686-B1 MOISTURE-CURABLE COMPOSITIONS COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-05-10 — — EP claimed
EP-3474046-B1 POLYMERIZABLE COMPOSITION FOR A MAKING A PLASTIC LENS AND PROCESS FOR PREPARING SUCH A LENS SKC CO LTD (KR) 2022-11-30 — — EP claimed
EP-3357950-B1 POLYMERIZABLE COMPOSITION FOR PLASTIC LENS AND METHOD OF PREPARING PLASTIC LENS USING SAME SKC CO LTD (KR) 2022-01-12 — — EP claimed
CN-108276555-B Polymerizable composition for plastic lens and method for producing plastic lens using same SKC株式会社 2021-11-05 — — CN claimed
CN-109293865-B Polymerizable composition for plastic lenses SKC株式会社 2021-09-24 — — CN claimed
US-10968309-B2 Polymerizable composition for a plastic lens SKC CO., LTD. (KR) 2021-04-06 — — US claimed
US-20200392278-A1 MOISTURE-CURING COMPOSITIONS COVESTRO DEUTSCHLAND AG (DE) 2020-12-17 — — US claimed
US-10865307-B2 Polymerizable composition for plastic lens and method of preparing plastic lens using same SKC CO.. LTD. (KR) 2020-12-15 — — US claimed
EP-3474046-A1 POLYMERIZABLE COMPOSITION FOR A PLASTIC LENS SKC Co., Ltd. (KR) 2019-04-24 — — EP claimed
US-20190112414-A1 POLYMERIZABLE COMPOSITION FOR A PLASTIC LENS SK PUCORE CO., LTD. (KR) 2019-04-18 — — US claimed
CN-109293865-A Polymerisable compound for glass lens SKC株式会社 2019-02-01 — — CN claimed
US-20180224576-A1 POLYMERIZABLE COMPOSITION FOR PLASTIC LENS AND METHOD OF PREPARING PLASTIC LENS USING SAME SKC CO., LTD. (KR) 2018-08-09 — — US claimed
EP-3357950-A1 POLYMERIZABLE COMPOSITION FOR PLASTIC LENS AND METHOD OF PREPARING PLASTIC LENS USING SAME SKC Co., Ltd. (KR) 2018-08-08 — — EP claimed
CN-108276555-A Glass lens polymerizable composition, polymerizable composition and the manufacturing method for using its glass lens SKC株式会社 2018-07-13 — — CN claimed
CN-105523874-A Preparation method of 2,2-dihalo-1,3-dicarbonyl derivatives ZHANGJIAGANG INST IND TECHNOLOGIES SOOCHOW UNIV 2016-04-27 — — CN claimed
CN-105461496-A Preparation method for 2-halogenated-1,3-dicarbonyl derivative CHINASUN SPECIALTY PRODUCTS CO LTD 2016-04-06 — — CN claimed
CN-105348060-A Preparation method of 1,2-diketone derivative CHINASUN SPECIALTY PRODUCTS CO LTD 2016-02-24 — — CN claimed
US-4268539-A INDIUM NITRATE-DIKETONE REACTION PRODUCT TOKYO DENSHI KAGAKU KABUSHIKI KAISHA (JP) 1981-05-19 — — US claimed
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