Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205874 | 0.92 | MAPK1 (0.44) | MAPK1ADORA3TSHRNPSR1ABCB1 | |
| SCHEMBL7210239 | 0.92 | ABCB1 (0.50) | MAPK1ADORA3TSHRNPSR1ABCB1 | |
| SCHEMBL3874062 | 0.91 | MAPK1 (0.56) | MAPK1ADORA3TSHRNPSR1ABCB1 | |
| SCHEMBL7211816 | 0.89 | TLR7 (0.44) | MAPK1ADORA3TSHRNPSR1ALDH1A1 | |
| SCHEMBL7205405 | 0.88 | MAPK1 (0.48) | MAPK1ADORA3TSHRNPSR1ABCB1 | |
| SCHEMBL7211567 | 0.88 | TSHR (0.44) | MAPK1ADORA3TSHRNPSR1ABCB1 | |
| SCHEMBL7208339 | 0.88 | ADORA3 (0.48) | MAPK1ADORA3TSHRNPSR1ADORA2A | |
| SCHEMBL7208584 | 0.87 | MAPK1 (0.47) | MAPK1ADORA3TSHRNPSR1ABCB1 | |
| SCHEMBL10174463 | 0.87 | L3MBTL1 (0.48) | MAPK1ADORA3TSHRNPSR1ABCB1 | |
| SCHEMBL7205545 | 0.87 | TLR7 (0.47) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1035123-B1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMA (JP) | 2003-08-20 | — | — | EP | disclosed |
| US-6329381-B1 | INTERFERONS, VIRICIDES AND ANTICARCINOGENIC AGENTS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |
| EP-1035123-A1 | NOVEL HETEROCYCLIC COMPOUNDS | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 2000-09-13 | — | — | EP | disclosed |