Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212922 | 1.00 | ATM (0.42) | ATMRAB9AKMT2ANPY5RABCC1 | |
| SCHEMBL7212919 | 1.00 | ATM (0.42) | ATMRAB9AKMT2ANPY5RABCC1 | |
| SCHEMBL7206585 | 1.00 | ATM (0.42) | ATMRAB9AKMT2ANPY5RABCC1 | |
| SCHEMBL7211321 | 0.90 | ATM (0.54) | ATMRAB9AKMT2ANPY5RABCC1 | |
| SCHEMBL7211318 | 0.90 | ATM (0.54) | ATMRAB9AKMT2ANPY5RABCC1 | |
| SCHEMBL7212235 | 0.83 | ATM (0.40) | ATMRAB9AKMT2ANPY5RABCC1 | |
| SCHEMBL7212232 | 0.83 | ATM (0.40) | ATMRAB9AKMT2ANPY5RABCC1 | |
| SCHEMBL4803067 | 0.82 | LSS (0.51) | ATMRAB9AKMT2ANPY5RLSS | |
| SCHEMBL4803072 | 0.82 | LSS (0.51) | ATMRAB9AKMT2ANPY5RLSS | |
| SCHEMBL4807825 | 0.82 | LSS (0.51) | ATMRAB9AKMT2ANPY5RLSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |