Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | CCR5 | P51681 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7211321 | 1.00 | ATM (0.54) | ATMTP53NPY5RCCR5RAB9A | |
| SCHEMBL7206585 | 0.90 | ATM (0.42) | ATMTP53NPY5RCCR5RAB9A | |
| SCHEMBL7212922 | 0.90 | ATM (0.42) | ATMTP53NPY5RCCR5RAB9A | |
| SCHEMBL7206586 | 0.90 | ATM (0.42) | ATMTP53NPY5RCCR5RAB9A | |
| SCHEMBL7212919 | 0.90 | ATM (0.42) | ATMTP53NPY5RCCR5RAB9A | |
| SCHEMBL4801680 | 0.82 | LSS (0.52) | ATMTP53NPY5RCCR5RAB9A | |
| SCHEMBL4801683 | 0.82 | LSS (0.52) | ATMTP53NPY5RCCR5RAB9A | |
| SCHEMBL7205441 | 0.78 | ABCC1 (0.37) | TP53RAB9AABCC1KMT2A | |
| SCHEMBL7205438 | 0.78 | ABCC1 (0.37) | TP53RAB9AABCC1KMT2A | |
| SCHEMBL7208986 | 0.75 | LMNA (0.40) | RAB9APOLBUSP30KMT2ACARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |