Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LSS | P48449 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7212232 | 1.00 | ATM (0.40) | ATMRAB9ANPY5RKMT2ALSS | |
| SCHEMBL7208470 | 0.91 | LSS (0.47) | ATMRAB9ANPY5RKMT2ALSS | |
| SCHEMBL7208465 | 0.91 | LSS (0.47) | ATMRAB9ANPY5RKMT2ALSS | |
| SCHEMBL7205075 | 0.90 | ALDH1A1 (0.46) | ATMRAB9ANPY5RKMT2ALSS | |
| SCHEMBL7210327 | 0.90 | HPGD (0.42) | ATMRAB9AALDH1A1UBE2MDCUN1D1 | |
| SCHEMBL7205235 | 0.90 | FPR3 (0.42) | ATMRAB9ANPY5RKMT2ALSS | |
| SCHEMBL7209436 | 0.90 | FPR3 (0.42) | ATMRAB9ANPY5RKMT2ALSS | |
| SCHEMBL7205073 | 0.90 | ALDH1A1 (0.46) | ATMRAB9ANPY5RKMT2ALSS | |
| SCHEMBL7206024 | 0.90 | LSS (0.48) | ATMRAB9ANPY5RKMT2ALSS | |
| SCHEMBL7209439 | 0.90 | FPR3 (0.42) | ATMRAB9ANPY5RKMT2ALSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311475-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002014267-A1 | NOVEL AMINOCYCLOHEXANE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-02-21 | — | — | WO | disclosed |