Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.41 |
| ▸ | DRD4 | P21917 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206597 | 1.00 | CCR1 (0.53) | CCR1CHRM2CCR5DRD2DRD4 | |
| SCHEMBL12121529 | 0.95 | CCR1 (0.56) | CCR1CHRM2CCR5DRD2DRD4 | |
| SCHEMBL14419980 | 0.93 | CCR1 (0.54) | CCR1CHRM2CCR5ALDH1A1LMNA | |
| SCHEMBL15478373 | 0.93 | CCR1 (0.54) | CCR1CHRM2CCR5ALDH1A1LMNA | |
| SCHEMBL10287667 | 0.93 | CCR1 (0.54) | CCR1CHRM2CCR5DRD2DRD3 | |
| SCHEMBL7210849 | 0.92 | CCR1 (0.63) | CCR1CHRM2CCR5DRD2DRD3 | |
| SCHEMBL7210846 | 0.92 | CCR1 (0.63) | CCR1CHRM2CCR5DRD2DRD3 | |
| SCHEMBL13617244 | 0.92 | CCR1 (0.53) | CCR1CHRM2CCR5ALDH1A1LMNA | |
| SCHEMBL14419981 | 0.90 | CCR1 (0.57) | CCR1CHRM2CCR5DRD2DRD4 | |
| SCHEMBL14419979 | 0.90 | CCR1 (0.52) | CCR1CHRM2CCR5ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9663537-B2 | Chemokine receptor antagonists and methods of use | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-05-30 | — | — | US | disclosed |
| US-6613905-B1 | Treating or preventing a disease associated with aberrant leukocyte recruitment and/or activation | MILLENNIUM PHARMACEUTICALS, INC. | 2003-09-02 | — | — | US | disclosed |