Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.46 |
| ▸ | PGK2 | P07205 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL7206389 | 0.97 | PGK1 (0.43) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL7206392 | 0.92 | ADORA2A (0.41) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL7206395 | 0.90 | ADORA2A (0.41) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL7207959 | 0.90 | PGK1 (0.44) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL7208447 | 0.89 | ADORA2A (0.47) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL6835034 | 0.88 | PGK1 (0.46) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL7203070 | 0.88 | ADORA3 (0.53) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL8100503 | 0.88 | ADORA3 (0.53) | ADORA2AADORA3ADORA2BADORA1 | |
| Formic Acid SCHEMBL7202921 | 0.86 | ADORA2A (0.47) | PGK1PGK2ADORA2AADORA3ADORA2B | |
| SCHEMBL7208180 | 0.84 | ADORA2A (0.54) | ADORA2AADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610665-B1 | Treatment of inflammatory diseases, asthma or chronic obstructive pulmonary disease | SMITHKLINE BEECHAM CORPORATION | 2003-08-26 | — | — | US | claimed |
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | claimed |