Serine

Serine

SCHEMBL7206811

Cc1ccc(S(=O)(=O)N[C@@H](CO)C(=O)O)cc1.N[C@@H](CO)C(=O)O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC1A3 P43003 1/20 0.57
SLC1A2 P43004 1/20 0.57
SLC1A1 P43005 1/20 0.57
TDP1 Q9NUW8 1/20 0.56
MMP2 P08253 11/20 0.55
MMP13 P45452 6/20 0.55
MMP3 P08254 3/20 0.55
MMP9 P14780 13/20 0.49
MMP1 P03956 3/20 0.49
MMP7 P09237 2/20 0.49
ALDH1A1 P00352 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C19 P33261 1/20 0.46
ITGB3 P05106 1/20 0.46
ITGA2B P08514 1/20 0.46
ADAMTS4 O75173 1/20 0.46
MMP8 P22894 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL35211007 0.92 TDP1 (0.64) SLC1A3SLC1A2SLC1A1TDP1MMP2
SCHEMBL1734695 0.92 TDP1 (0.64) SLC1A3SLC1A2SLC1A1TDP1MMP2
SCHEMBL5193396 0.92 TDP1 (0.64) SLC1A3SLC1A2SLC1A1TDP1MMP2
SCHEMBL8445758 0.84 MMP2 (0.76) SLC1A3SLC1A2SLC1A1TDP1MMP2
SCHEMBL7337519 0.81 TDP1 (0.63) SLC1A3SLC1A2SLC1A1TDP1MMP2
SCHEMBL4041728 0.81 TDP1 (0.63) SLC1A3SLC1A2SLC1A1TDP1MMP2
Hydrochloric Acid SCHEMBL7649402 0.80 TDP1 (0.61) SLC1A3SLC1A2SLC1A1TDP1MMP2
SCHEMBL3392197 0.80 TDP1 (0.64) SLC1A3SLC1A2SLC1A1TDP1MMP2
SCHEMBL3397101 0.80 TDP1 (0.64) SLC1A3SLC1A2SLC1A1TDP1MMP2
SCHEMBL3427026 0.80 TDP1 (0.64) SLC1A3SLC1A2SLC1A1TDP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030195159-A1 HIV protease inhibitors based on amino acid derivatives TAIMED BIOLOGICS, INC. (TW) 2003-10-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195159-A1 HIV protease inhibitors based on amino acid derivatives ANPEP, PEPD, XPNPEP1 SLC1A3 139/4885SLC1A2 291/4885SLC1A1 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.