Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 14/20 | 0.76 |
| ▸ | MMP13 | P45452 | 12/20 | 0.76 |
| ▸ | MMP3 | P08254 | 10/20 | 0.76 |
| ▸ | MMP9 | P14780 | 7/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | MMP1 | P03956 | 3/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL35211007 | 0.92 | TDP1 (0.64) | MMP2MMP13MMP3MMP9TDP1 | |
| SCHEMBL5193396 | 0.92 | TDP1 (0.64) | MMP2MMP13MMP3MMP9TDP1 | |
| SCHEMBL1734695 | 0.92 | TDP1 (0.64) | MMP2MMP13MMP3MMP9TDP1 | |
| SCHEMBL8448575 | 0.86 | MMP2 (0.67) | MMP2MMP13MMP3MMP9TDP1 | |
| SCHEMBL8445799 | 0.85 | MMP2 (0.86) | MMP2MMP13MMP3MMP9TDP1 | |
| Serine SCHEMBL7206811 | 0.84 | SLC1A3 (0.57) | MMP2MMP13MMP3MMP9TDP1 | |
| SCHEMBL8449058 | 0.83 | MMP2 (0.67) | MMP2MMP13MMP3MMP9TDP1 | |
| SCHEMBL2904532 | 0.83 | MMP2 (0.81) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL8449004 | 0.82 | MMP9 (0.75) | MMP2MMP13MMP3MMP9MMP1 | |
| SCHEMBL8450205 | 0.82 | MMP9 (0.75) | MMP2MMP13MMP3MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | claimed |
| EP-0915086-A1 | PHENYLSULFONAMIDE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-05-12 | — | — | EP | disclosed |