Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | FABP3 | P05413 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 9/20 | 0.35 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | RARG | P13631 | 6/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | HMGCR | P04035 | 1/20 | 0.33 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7206959 | 0.86 | GLRA1 (0.39) | SRD5A2GLRA1SOAT2MYCSOAT1 | |
| SCHEMBL7206928 | 0.78 | FABP3 (0.41) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL7206867 | 0.78 | SRD5A2 (0.38) | SRD5A2FABP3FABP4GLRA1RXRA | |
| SCHEMBL7109323 | 0.76 | FABP3 (0.39) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL8498111 | 0.76 | FABP3 (0.52) | SRD5A2FABP3FABP4GLRA1RXRA | |
| SCHEMBL7108814 | 0.70 | FABP3 (0.41) | FABP3FABP4FABP5GABRA1GABRB2 | |
| SCHEMBL8706010 | 0.69 | FABP3 (0.38) | FABP3FABP4FABP5SOAT2MYC | |
| SCHEMBL2361439 | 0.69 | GSK3B (0.42) | — | |
| SCHEMBL7104863 | 0.69 | FABP3 (0.40) | FABP3FABP4FABP5GABRA1GABRB2 | |
| SCHEMBL7105200 | 0.68 | FABP3 (0.39) | FABP3FABP4RXRAPPARGRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |