Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.40 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.40 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109323 | 0.85 | FABP3 (0.39) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7206347 | 0.85 | GABRA1 (0.43) | SOAT2MYCSOAT1MAP2K3GABRA1 | |
| SCHEMBL7207657 | 0.80 | FABP3 (0.44) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7206870 | 0.78 | SRD5A2 (0.39) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7206404 | 0.78 | SOAT2 (0.40) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7207662 | 0.77 | FABP4 (0.58) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7206911 | 0.77 | HPGD (0.32) | — | |
| SCHEMBL7206924 | 0.76 | SOAT2 (0.39) | FABP3FABP4SOAT2MYCSOAT1 | |
| SCHEMBL7212859 | 0.75 | AKR1B1 (0.45) | — | |
| SCHEMBL7620745 | 0.73 | FABP3 (0.39) | FABP3FABP4SOAT2MYCSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841913-B1 | USE OF SULFAMIC ACID DERIVATIVES, ACYL SULFONAMIDES OR SULFONYL CARBAMATES FOR THE MANUFACTURE OF A MEDICAMENT FOR LOWERING LIPOPROTEIN LEVELS | WARNER LAMBERT CO (US) | 2003-02-05 | — | — | EP | claimed |