Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | CRHBP | P24387 | 2/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTPRF | P10586 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258298 | 0.84 | MAPT (0.71) | MITFMAPTMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL2989250 | 0.83 | MAPT (0.70) | MITFMAPTMEN1KMT2ATDP1 | |
| SCHEMBL6815029 | 0.81 | KMT2A (0.70) | MITFMAPTMEN1KMT2ALMNA | |
| SCHEMBL6259160 | 0.80 | MITF (0.59) | MITFMAPTMEN1KMT2ATDP1 | |
| SCHEMBL3667563 | 0.80 | MITF (0.70) | MITFMAPTMEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL2992198 | 0.79 | MITF (0.58) | MITFMAPTMEN1KMT2ATDP1 | |
| SCHEMBL9683104 | 0.79 | MAPT (0.55) | MITFMAPTMEN1KMT2ATDP1 | |
| SCHEMBL6691544 | 0.77 | PTPRF (0.51) | MAPTMEN1KMT2ATDP1LMNA | |
| SCHEMBL27565507 | 0.77 | PTPRF (0.71) | MITFMAPTMEN1KMT2APTPRF | |
| SCHEMBL14950713 | 0.77 | PTPRF (0.71) | MITFMAPTMEN1KMT2APTPRF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076388-A2 | BIS-ANILINE DERIVATIVES USEFUL AS POTASSIUM CHANNELS MODULATORS | 4SC AG (DE) | 2003-09-18 | — | — | WO | disclosed |