Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | MEN1 | O00255 | 10/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 2/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815029 | 0.82 | KMT2A (0.70) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL9701292 | 0.80 | MAPT (0.74) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7206916 | 0.79 | MITF (0.62) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL9681404 | 0.74 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL17538567 | 0.74 | MEN1 (0.57) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL18610096 | 0.72 | MAPT (0.71) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL15367493 | 0.72 | MAPT (0.56) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL3750282 | 0.71 | MEN1 (0.70) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL9213419 | 0.71 | HSD17B10 (0.57) | MAPTMEN1KMT2AALDH1A1CRHBP | |
| SCHEMBL11656718 | 0.71 | HSD17B10 (0.60) | MAPTMEN1KMT2AALDH1A1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |