Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.49 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168517 | 0.83 | PTGS2 (0.62) | PTGS2PTGS1GPR17 | |
| SCHEMBL6170778 | 0.82 | PTGS2 (0.76) | PTGS2PTGS1GPR17 | |
| SCHEMBL6170571 | 0.81 | PTGS2 (0.71) | PTGS2PTGS1GPR17 | |
| SCHEMBL6170376 | 0.81 | PTGS2 (0.65) | PTGS2PTGS1GPR17 | |
| SCHEMBL8120959 | 0.81 | PTGS2 (0.57) | PTGS2PTGS1GPR17 | |
| SCHEMBL6169260 | 0.81 | PTGS2 (0.59) | PTGS2PTGS1GPR17 | |
| SCHEMBL6169948 | 0.81 | PTGS2 (0.73) | PTGS2PTGS1GPR17 | |
| SCHEMBL6170593 | 0.79 | PTGS2 (0.59) | PTGS2PTGS1GPR17 | |
| SCHEMBL6170181 | 0.79 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL6169641 | 0.79 | PTGS2 (0.59) | PTGS2PTGS1GPR17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |