Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 20/20 | 0.45 |
| ▸ | RXRB | P28702 | 12/20 | 0.45 |
| ▸ | RXRG | P48443 | 12/20 | 0.45 |
| ▸ | RARG | P13631 | 6/20 | 0.45 |
| ▸ | RARA | P10276 | 4/20 | 0.45 |
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8597944 | 0.91 | RXRA (0.37) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7208544 | 0.86 | RXRA (0.51) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7061866 | 0.80 | RXRA (0.63) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7212158 | 0.80 | RXRA (0.63) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7061862 | 0.80 | RXRA (0.63) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7208727 | 0.78 | RXRA (0.71) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7208494 | 0.78 | RXRA (0.71) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7208488 | 0.78 | RXRA (0.71) | RXRARXRBRXRGRARGRARA | |
| SCHEMBL7212191 | 0.77 | RXRA (0.41) | RXRARARGRARARARBPPARG | |
| SCHEMBL8595293 | 0.77 | RXRA (0.41) | RXRARXRBRXRGRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610877-B1 | Treating photo and/or age damaged skin | HOFFMAN-LA ROCHE INC. | 2003-08-26 | — | — | US | disclosed |
| US-5700836-A | TOPICALLY ADMINISTERING TO TREAT PHOTODAMAGED SKIN | HOFFMANN-LA ROCHE INC. (US) | 1997-12-23 | — | — | US | disclosed |