Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 10/20 | 0.41 |
| ▸ | HNF4A | P41235 | 2/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARB | P10826 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213506 | 0.86 | RARA (0.44) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL7207780 | 0.83 | RARA (0.48) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL8905399 | 0.83 | RXRA (0.34) | RXRAPPARGNR1H3ALDH1A1 | |
| SCHEMBL7212372 | 0.83 | RXRA (0.34) | RXRAPPARGNR1H3ALDH1A1 | |
| SCHEMBL6915189 | 0.81 | RARA (0.60) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL7124980 | 0.80 | RARA (0.61) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL7124972 | 0.80 | RARA (0.61) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL6915866 | 0.78 | RARA (0.64) | RXRAHNF4ARARARARBRARG | |
| SCHEMBL7207118 | 0.77 | RXRA (0.45) | RXRARARARARBRARGPPARG | |
| SCHEMBL7212192 | 0.76 | RXRA (0.33) | RXRAPPARGNR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610877-B1 | Treating photo and/or age damaged skin | HOFFMAN-LA ROCHE INC. | 2003-08-26 | — | — | US | disclosed |