Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 12/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 6/20 | 0.38 |
| ▸ | CTSS | P25774 | 6/20 | 0.38 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687294 | 0.89 | CTSK (0.45) | CTSKCACNA1BCTSLCTSSKMT2A | |
| SCHEMBL7565325 | 0.89 | CTSK (0.45) | CTSKCACNA1BCTSLCTSSKMT2A | |
| SCHEMBL5099268 | 0.89 | CTSK (0.41) | CTSKCACNA1BCTSLCTSSCAPN1 | |
| SCHEMBL7426616 | 0.88 | CTSK (0.44) | CTSKCACNA1BCTSLCTSSCTSB | |
| SCHEMBL5096443 | 0.88 | CTSK (0.41) | CTSKCACNA1BCTSLCTSSCAPN1 | |
| SCHEMBL5096704 | 0.87 | CACNA1B (0.42) | CTSKCACNA1B | |
| SCHEMBL14131846 | 0.87 | CACNA1B (0.42) | CTSKCACNA1B | |
| SCHEMBL7427560 | 0.87 | CTSK (0.41) | CTSKCTSLCTSSCAPN1CTSB | |
| SCHEMBL6596974 | 0.86 | CTSK (0.55) | CTSKCTSLCTSSCTSBCTSV | |
| SCHEMBL6402928 | 0.85 | CTSK (0.46) | CTSKCTSLCTSSCTSBCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229915-A4 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-05-14 | — | — | EP | disclosed |
| EP-1229915-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001034160-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-05-17 | — | — | WO | disclosed |