Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207146 | 0.80 | L3MBTL1 (0.33) | — | |
| SCHEMBL4435493 | 0.67 | L3MBTL1 (0.39) | ALDH1A1 | |
| SCHEMBL23850269 | 0.67 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL5750257 | 0.67 | ALDH1A1 (0.47) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL25312951 | 0.66 | L3MBTL1 (0.38) | ALDH1A1 | |
| SCHEMBL5002021 | 0.66 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL3424789 | 0.64 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL27703960 | 0.62 | GAA (0.47) | ALDH1A1 | |
| SCHEMBL28088382 | 0.62 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL11695424 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE38333-E1 | Making tenofovir analogs and salts; use as viricides for HIV, retroviruses | GILEAD SCIENCES, INC. | 2003-11-25 | — | — | US | disclosed |
| EP-0915894-B1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES INC (US) | 2003-05-14 | — | — | EP | disclosed |
| US-6069249-A | CHEMICAL INTERMEDIATES; DETECTION LABELS FOR NUCLEOTIDE PROBES | GILEAD SCIENCES, INC. (US) | 2000-05-30 | — | — | US | disclosed |
| US-6043230-A | Use of tenofovir disoproxil fumarate in treatment of HIV | GILEAD SCIENCES, INC. (US) | 2000-03-28 | — | — | US | disclosed |
| US-5977089-A | ORALLY ADMINISTERING TENOFOVIR DERIVATIVES | GILEAD SCIENCES, INC. (US) | 1999-11-02 | — | — | US | disclosed |
| US-5922695-A | COMPOUNDS CONTAINING CARBONATE OR CARBAMATE GROUPS | GILEAD SCIENCES, INC. (US) | 1999-07-13 | — | — | US | disclosed |
| EP-0915894-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004569-A1 | NUCLEOTIDE ANALOGS | GILEAD SCIENCES, INC. (US) | 1998-02-05 | — | — | WO | disclosed |